Some recent advances in covariate modeling methodology by the Uppsala Pharmacometric Research Group
Authors |
Title |
Reference |
Åsa Johansson and Mats O Karlsson |
Multiple imputation of missing covariates in NONMEM and evaluation of its sensitivity to η-shrinkage |
WCoP 2012 |
Vijay Ivaturi, Ron Keizer and Mats O. Karlsson |
A full random effects model for characterising covariate relations |
WCoP 2012 |
Andrew C. Hooker and Mats O. Karlsson |
The Kaplan-Meier Mean Covariate plot (KMMC): a new diagnostic for covariates in time-to-event models. |
PAGE 2012 |
Takayuki Katsube, Akash Khandelwal, Andrew C Hooker, E. Niclas Jonsson, Mats O Karlsson |
Characterization of Stepwise Covariate Model Building Combined with Cross-Validation |
PAGE 2012 |
Mats O Karlsson |
A full model approach based on the covariance matrix of parameters and covariates |
PAGE 2012 |
Khandelwal A, Harling K, Jonsson EN, Hooker AC, Karlsson MO. |
A fast method for testing covariates in population PK/PD Models. |
AAPS J. 2011 ;13:464-72. |
Bergstrand M, Hooker AC, Wallin JE, Karlsson MO. |
Prediction-corrected visual predictive checks for diagnosing nonlinear mixed-effects models. |
AAPS J. 2011 ;13:143-51. |
Paul G. Baverel, Radojka M. Savic, Scott F. Marshall, Mats O. Karlsson |
A novel covariate search method intended for PKPD models with nonparametric parameter distributions |
PAGE 2011 |
Takayuki Katsube, Akash Khandelwal, Kajsa Harling, Andrew C Hooker, Mats O Karlsson |
Evaluation of Stepwise Covariate Model Building Combined with Cross-Validation |
PAGE 2011 |
Ron J Keizer, Akash Khandelwal, Andrew C Hooker, Mats O Karlsson |
The bootstrap of Stepwise Covariate Modeling using linear approximations |
PAGE 2011 |
Akash Khandelwal, Andrew C Hooker, and Mats O Karlsson |
Influence of Correlated Covariates on Predictive Performance for Different Models |
PAGE 2011 |
Vijay D Ivaturi, Andrew C Hooker, Mats O Karlsson |
Selection Bias in Pre-Specified Covariate Models |
PAGE 2011 |
Åsa M. Johansson, Mats O. Karlsson |
Comparison of methods for handling missing covariate data |
PAGE 2011 |
Akash Khandelwal, Kajsa Harling, E Niclas Jonsson, Andrew C Hooker, Mats O Karlsson |
Covariate Model Building Using Linear Approximations |
PAGE 2010 |
Savic RM, Karlsson MO. |
Importance of shrinkage in empirical bayes estimates for diagnostics: problems and solutions. |
AAPS J. 2009 ;11:558-69. |